Literature |
Suggested reading in PDF |
Acrobat |
History |
Historical Overview of Drug Discovery (Kahn, 2012) |
PDF |
General |
The Global Drug Gap |
PDF |
Employment |
Biopharmaceutical Jobs |
PDF |
Biological Concept |
Inhibiting the p53-MDM2 Interaction |
PDF |
Biological Concept |
Hallmarks of Cancer |
PDF |
Biological Concept |
Osteoporosis Tagets |
PDF |
Validation |
Application of DNA Microarrays in Biology (Stoughton) |
PDF |
Validation |
DNA Microarrays |
PDF |
Validation |
Unravelling Novel Intracellular Pathways in Cell Based Assays |
PDF |
Validation |
Cell-based Assay for Ion-channel Targets |
PDF |
Validation |
gp41 validation as HIV target |
PDF |
Validation |
Inhibition of HIV Fusion |
PDF |
Validation |
Dissecting HIV-1 through RNAi |
PDF |
Validation |
From peptides to drugs via phage display |
PDF |
Validation |
Developments in Microarray Technologies |
PDF |
Validation |
Proteomics by Mass Spectrometry |
PDF |
Validation |
SNP: Introduction |
PDF |
Validation |
Single Nucleotide Polymorphisms: Review |
PDF |
Validation |
SNP: Crohn's Disease |
PDF |
Software |
Introduction to Mathematica |
PDF |
Targets |
Deformylase |
PDF |
Targets |
Targets for parasite diseases |
PDF |
Targets |
Acetylcholine receptors |
PDF |
Targets |
Protein Kinases as Drug Targets |
PDF |
Targets |
Oprhan GPCR research (Chung et al, 2008) |
PDF |
Strategies |
Multiple Sclerosis: Current Treatment Approaches |
PDF |
Leads |
Farnesyl:Protein Transferase Inhibitors |
PDF |
Leads |
The Discovery of Fluoxetine Hydrochloride |
PDF |
Leads |
Glyco- and Peptidomimetic Combinatorial Libraries |
PDF |
Leads |
HIV Protease Inhibitors: TD Review |
PDF |
CombiChem |
Discovery of Sorafenib (Wilhelm, 2006) |
PDF |
CombiChem |
Combinatorial 1,4-benzodiazepine library (Bunin et al, 1994) |
PDF |
ADME |
Pharmacokinetics Review |
PDF |
ADME |
Flourine for increasing chemical and metabolic stability |
PDF |
Enzymes |
Historical Review of Enzymology |
PDF |
Enzymes |
Entropy in Enzyme Catalysis: Page and Jencks |
PDF |
Enzymes |
Entropy in Enzyme Catalysis: Warshel |
PDF |
Enzymes |
Entropy in Bimolecular Association: Yu & Privalov |
PDF |
Enzymes |
Near Attack Conformers: Bruice and Benkovic |
PDF |
Enzymes |
Enzymes: Modern Rate Theories |
PDF |
LBDD |
Molecular Similarity: Bender and Glen |
PDF |
LBDD |
CTFile Formats: Description of MOL and SDF files |
PDF |
SBDD |
Recent developments in structure-based drug design |
PDF |
SBDD |
High-throughput docking: thyroid hormone receptor |
PDF |
QSAR |
Historical Review: Kubinyi |
PDF |
QSAR |
Historical Review: Selassie |
PDF |
Prodrugs |
Targeted ProDrug Strategies |
PDF |
Prodrugs |
Pronucleotides - Efficient Delivery of Nucleoside Monophosphates |
PDF |
Pharmacogenomics |
Pharmacogenomics: Review |
PDF |
Pharmacogenomics |
Pharmacogenomics and Pharmacogenetics: Impact |
PDF |
Pharmacogenomics |
Molecular Diagnostics as Predictive Tool |
PDF |
Antisense Therapy |
Delivery of Antisense Therapeutics |
PDF |
Proteins as Therapeutics |
Osslund: G-CSF Interactionw w/ Receptor |
PDF |
Proteins as Therapeutics |
Osslund: G-CSF Isotope-Edited FTIR Studies |
PDF |
Proteins as Therapeutics |
Osslund: Neurotrophic Factor Studies |
PDF |
Strategic Managment |
Strategic Trends in the Drug Industry |
PDF |