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Newsletter - Winter 2012


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California Los Padres ACS




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Travel Awards for Undergraduates:
A Program to Support Students

Updated February, 2012


Next Event


Rebecca Anderson, Ph.D.

Freelance Writer and

Author of Career Opportunities in Clinical Drug Research

Speaking on

Finding New Drugs: The Path from Test Tube to the Pharmacy

1 pm.

Saturday, February 11, 2012

Building 52 Room E-26

Cal Poly State University, San Luis Obispo

Light refreshments will be served.

Abstract: Current industry statistics estimate that it takes fifteen years and nearly $1 billion to bring a new drug to market, but most consumers are unaware—and even skeptical—of the extensive efforts involved in finding and successfully developing these products. This presentation looks inside the black box, sharing an insider’s view of pharmaceutical research and development and answering several commonly asked questions: Where does a chemist get ideas for synthesizing an innovative drug? Why are animals still used in drug research? Why can’t scientists and clinicians work faster? And why can’t they do their job better and cheaper? In the course of describing the drug development activities, this presentation will highlight the range of chemistry subspecialties employed in moving a drug from the lab bench to the pharmacy shelf.


Rebecca Anderson
has worked in the biopharmaceutical industry for more than 25 years in jobs spanning pharmaceuticals, biotechnology, medical devices, and contract research organizations. She holds a BA degree in chemistry from Coe College and a Ph.D. in pharmacology from Georgetown University. Following postdoctoral training at the University of Toronto, she held academic appointments at the George Washington University Medical Center and the University of Michigan School of Public Health. She subsequently held positions of increasing responsibility in pharmaceutical R&D at Parke-Davis & Company, Boehringer Ingelheim Pharmaceuticals, Miravant Pharmaceuticals, and Amgen. Dr. Anderson currently works as a freelance technical writer and is the author of Career Opportunities in Clinical Drug Research.


Directions:

From the North Take Hwy 101 South to the Monterey Street Exit (204). Turn Right onto Buena Vista Avenue and then an immediate Left onto Loomis Street. Take the 3rd Right onto Grand Avenue. Use the general parking lot near Performing Arts Center or proceed to Perimeter Road at the core of the campus and turn right. Faculty parking lots can be found along Perimeter Road. Unless specifically posted, permit requirements are not enforced on weekends.

From the South Take Hwy 101 North the Grand Avenue Exit (203D). Turn Left onto Grand Avenue. Use the general parking lot near Performing Arts Center or proceed to Perimeter Road at the core of the campus and turn right. Faculty parking lots can be found along Perimeter Road. Unless specifically posted, permit requirements are not enforced on weekends.

(For a campus map go to http://maps.calpoly.edu/printable_maps.html)





Previous Event
Executive Committee Meeting
Saturday, January 7, 10am
Tynan Group
2927 De la Vina Street, Suite A
Santa Barbara, California
All active members may attend this business meeting.


Previous Event

Annual Holiday Wine Tasting
Mosby



was held

Noon, Saturday, December 10, 2011

at

Mosby Winery and Vineyards

9496 Santa Rosa Rd, Buellton


 

The cost for the event was $15 per person.

 

A variety of international cheeses and homemade soups will accompany the wine tasting.

 

While Bill Mosby's specialty is the growing and vinification of fine Italian varietal wines, he also makes award-winning grappa, wild plum and raspberry distillatos. His experienced palate and careful, ongoing search for interesting new varietals have resulted in vintage after vintage of award-winning Sangiovese, Nebbiolo, Pinot Grigio and more. And then there’s his latest addition, Dolcetto — the everyday wine of Piemonte.

When Bill and Jeri purchased the old de la Vega land in the early 1970s, the first thing Bill did was plant vines. "Noah did that," he says quietly. "First thing he did. Plant a vineyard." Among those early Mosby wines was Gewürztraminer, Jeri’s favorite. "It’s still my favorite," says Jeri. "I’m going to miss having it in the tasting room." The Mosby’s first commercial wines were bottled under the Vega label, named after the old land grant. Bill’s wine began to gain industry attention, and a following of Mosby wine enthusiasts continued to develop. In 1986, at his family’s insistence, Bill changed the Vega label to reflect the Mosby name and winemaking philosophy.

Over the years the Mosby vineyards have expanded, the wines have evolved; a Mosby style has reached maturity. A part-time grower and winemaker all of his adult life, Bill Mosby finally made the career move to full-time grower and winemaker in 1998. A successful dentist for over 40 years, William M. Mosby, DMD, became Bill Mosby, full-time winemaker — artist of the vine.

 

For more information and reservation forms go to This Link email calpacs@chem.ucsb.edu, or call James Pavlovich at 805-893-4252.

 

For a map, directions and more info on Mosby Wines and Vineyards go to their web site at www.mosbywines.com

 

Please make your reservations by Monday, December 5, 2011.

 

Reserve Early as Space is Limited.


Previous Event

Fall Luncheon and 50 Year Member Meeting

will be held

Noon, Saturday, October 22, 2011

at Stella Mare’s Restaurant, 50 Los Patos Way Santa Barbara, CA.

 

The cost for lunch will be $25 per person

or $15 for students and former 50 year honorees.

The Menu will include a choice of entrée, Roasted chicken breast (with a twice baked potato and roasted Roma tomatoes) or Penne (with artichoke hearts, wild mushrooms, and fresh tomatoes in a white wine garlic sauce), and Black Forest chocolate cake for dessert.

 

The Featured Speaker will be the 50 year honoree

J. Thomas Gerig

Professor Emeritus, Department of Chemistry and Biochemistry, UCSB.

Speaking on:


Understanding Peptide-Solvent Interactions through NMR and MD.

 

Many laboratory operations involve dissolving a peptide or protein in a mixture of water and a small organic molecule such as acetonitrile or trifluoroethanol. Changes in biopolymer conformation, solubility, electrophoretic mobility, and propensity to self-assemble can be produced in this way. Direct interactions between the components of the solvent and the solute are presumably involved to some extent in provoking such changes. Our lab has been using intermolecular nuclear Overhauser experiments to probe peptide-solvent interactions in water-organic mixtures. There are indications of specific solvent interactions at sites of the solute from these experiments. However, the current status of theory often does not permit a clean interpretation of an observed effect since either changes in local solvent composition or changes in the local dynamics of solvent molecules can produce equivalent experimental observations. We have turned to molecular dynamics (MD) simulations in an attempt to untangle these considerations. After a qualitative overview of the experiments, the talk will describe results of all-atom simulations of the peptide hormone [val5]angiotensin dissolved in 25% methanol-water and compare the intermolecular Overhauser effects calculated from these to experimental observations. Insights into the microscopic nature of this system and the details of peptide-solvent interactions arise.


John Thomas Gerig received a B.A. degree from the College of Wooster in 1960 and the Ph.D. from Brown University in 1964. Following two years as a post-doctoral fellow at the California Institute of Technology, working in J. D. Roberts’ lab,  he joined the then emerging Department of Chemistry at UCSB in 1966. He retired 40 years later as Professor Emeritus but continues to work in the department as Research Professor. He received a Research Career Development Award from the NIH and is a fellow of the AAAS and the Japan Association for the Promotion of Science. He was an ACS tour speaker in 1990, 1997 and 1998. Gerig is a recreational cyclist and has commuted daily to the UCSB campus by bike since 1982.  His wife of 50 years, Betty, plays an essential role in his activities, scientific and otherwise.

 

For more information email calpacs@chem.ucsb.edu,

or call David Marten at 805-565-6189


Please fill out the linked form and return with your check by Friday, October 14.
Directions to Stella Mare can be found on this form.
Tom Gerig




Postcard


Previous Event
Executive Committee Meeting
Saturday, May 14, 10am
TynanGroup
2927 De la Vina Street, Suite A
Santa Barbara, California
All active members may attend this business meeting.



Previous Event

Richard W. Hurst Ph.D.
Professor Emeritus,
California State University - Los Angeles

Speaking on
The Duality of Lead in the Environment:  
Environmental Bane and Boon [Good Cop – Bad Cop]


2 pm.
Sunday, April 17, 2011
SLO County Library Community Room
995 Palm Street, San Luis Obispo

Light refreshments will be served.

Abstract: The element lead (chemical symbol, Pb, from plumbum) has historical uses that date back 6000 years.  Lead’s toxic nature has also been known for centuries, however, its desirable properties have often “tipped the scales” when decisions arose as to whether or not lead should be used in a particular product.  For example, the Romans used it due to its malleability, forming lead pipes for water transport and its sweet taste when formed into goblets from which wine was consumed.  More recently, addition of lead additives to gasoline were determined to stop engine “knocking”; hence, the leaded gasoline era emerged along with the result---long-term environmental lead pollution.  Now that we are dealing with lead pollution, given it does not degrade (i.e., break down) in the environment, how do we assess the source or sources of the lead?  We do this with the positive aspects of lead, its isotopes.  Isotope ratios of lead allow us to:  estimate ages of leaded gasoline releases; assess why the common garden snail “outsmarts” us with regard to potential lead poisoning; and determine why lead based paint is not always, as some suspect, the “bad guy on the block.”  The element lead definitely has a dual nature---being both toxic to life, but also, via its isotopes, providing a means to resolve the problems created by its use.

Dr. Hurst is a Professor Emeritus of Geology and Geochemistry at California State University, Los Angeles where he has instructed and performed research since 1978.  He is also an Adjunct Professor of Environmental Geology, Mineralogy, and Petrology at California Lutheran University.  His primary research interests have centered on forensic environmental isotope geochemistry and mineralogy.  Since 1980, he has studied the use of naturally-occurring, stable isotopes, especially those of lead, as a means of tracing the sources of hydrocarbon and other types of contamination in the environment.  He is recognized for his development of the ALAS Model which employs lead isotopes to estimate the age of leaded gasoline releases; the model is used throughout the United States, Canada, and South America. 

Directions:
From the North Take Hwy 101 South to the Olive St/Santa Rosa Exit (203a). Merge Right onto Olive Street, then Turn Right onto Santa Rosa.  In 0.3 miles Turn Right onto Palm Street.  Drive 1 block to the SLO library on you left.  

From the South Take Hwy 101 North to the Osos Street Exit (203a).  Merge Right onto Osos Street.  In 0.3 miles Turn Right onto Palm Street.  The SLO Library will be on your left.

A parking garage is located adjacent to the library.  Alternately, street parking is free on Sundays.



Previous Event
ACS Tour Speaker
Dr. Lisa Balbes
Balbes Consultants
 
Nontraditional Careers for Chemists
 
When: Thursday, March 24 at 6:30pm
Where: Room 210, Winter Hall, Westmont College, Santa Barbara
Admission is free. Light refreshments will be served before the talk.
 
ABTRACT: A chemistry background prepares you for much more than just a laboratory career. The broad science education, analytical thinking, research methods, and other skills learned are of value to a wide variety of types of employers, and essential for a plethora of types of positions. By understanding your own personal values and interests, you can make informed decisions about what career paths to explore, and identify positions that match your needs. This talk will discuss a variety of nontraditional careers for chemists, such as chemical information, patent work, technical writing, education, human resources, sales and marketing, and much more. We will discuss typical tasks, education or training requirements, and personal characteristics that make for a successful career in each field, illustrated with specific examples. Valuable tips and advice about planning career transitions will also be provided.
 
Dr. Lisa M. Balbes founded Balbes Consultants (formerly Osiris Consultants) in 1992. Balbes Consultants provides scientific writing services, including documentation, grants, proposals and more for over 50 client companies. She was chair of the St. Louis Section of the American Chemical Society in 2002, receiving an Outstanding Local Section Achievement Award and a Salute to Excellence Award for her work there. She is also very involved in career development for chemists, has been a volunteer career consultant for ACS since 1993, presenter since 2002, and is the author of Nontraditional Careers for Chemists, published by Oxford University Press in 2006. Dr. Balbes obtained a Ph.D. in chemistry from the University of North Carolina at Chapel Hill, and her undergraduate degrees in chemistry and psychology from Washington University in St Louis. For more information, see www.balbes.com, or contact her at lisa@balbes.com.

(directions on this link)

Lisa Balbes

Previous Event

A Tour of

Nusil

10 am to Noon
Saturday, January 29, 2011

1050 Cindy Lane
Carpinteria, California
(see directions here)
Refreshments will be served.
The cost for the event will be $5 per person.

Space is limited. Attendees must be pre-registered by Wednesday, January 26, 2011.

 on the form.

 

Nusil #1


Nusil #2

NuSil Technology is a global manufacturer of silicone compounds for aerospace, healthcare, electronics and photonics applications requiring precise and predictable materials performance. ISO 9001-certified since 1994, NuSil operates state-of-the-art laboratories and processing facilities in the United States. With more than 400 employees worldwide, NuSil Technology specializes in providing on-site, in-person application engineering support.

 

Founded in 1979, NuSil focuses exclusively on silicone technology and related process development. The company comprises hundreds of research, manufacturing and engineering professionals perfecting silicone as the material of choice based upon its vast array of unique applications.

For more information email calpacs@chem.ucsb.edu, or call James Pavlovich at 805-893-4252.







Regional Student Affiliates of the American Chemical Society (SAACS)

SAACS, Cal Poly

SAACS, UCSB

SAACS, Westmont College



 
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